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Concept information

Preferred term

Decitabine  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 2' Deoxy 5 azacytidine
  • 2'-Deoxy-5-azacytidine
  • 5 Aza 2' deoxycytidine
  • 5-Aza-2'-deoxycytidine
  • 5-AzadC
  • 5AzadC
  • 5 Azadeoxycytidine
  • 5-Azadeoxycytidine
  • AzadC Compound
  • Compound, AzadC

Scope note

  • An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.

History note

  • 2019 (1977)

In other languages

URI

http://www.yso.fi/onto/mesh/D000077209

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