Concept information
Preferred term
Decitabine
Type
-
Topical Descriptor
Broader concept
Entry terms
- 2' Deoxy 5 azacytidine
- 2'-Deoxy-5-azacytidine
- 5 Aza 2' deoxycytidine
- 5-Aza-2'-deoxycytidine
- 5-AzadC
- 5AzadC
- 5 Azadeoxycytidine
- 5-Azadeoxycytidine
- AzadC Compound
- Compound, AzadC
Scope note
- An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.
History note
- 2019 (1977)
In other languages
-
Finnish
-
decitabinum
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000077209
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