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Concept information

Fluids and Secretions > Bodily Secretions > Venoms > Exenatide
Biological Factors > Toxins, Biological > Venoms > Exenatide
Complex Mixtures > Venoms > Exenatide
Amino Acids, Peptides, and Proteins > Peptides > Exenatide

Preferred term

Exenatide  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • AC 2993
  • AC 2993 LAR
  • Bydureon
  • Byetta
  • Exendin-4
  • ITCA 650

Scope note

  • A synthetic form of exendin-4, a 39-amino acid peptide isolated from the venom of the GILA MONSTER lizard (Heloderma suspectum). Exenatide increases CYCLIC AMP levels in pancreatic acinar cells and acts as a GLUCAGON-LIKE PEPTIDE-1 RECEPTOR (GLP-1) agonist and incretin mimetic, enhancing insulin secretion in response to increased glucose levels; it also suppresses inappropriate glucagon secretion and slows gastric emptying. It is used as an anti-diabetic and anti-obesity agent.

History note

  • 2019 (1992)

In other languages

URI

http://www.yso.fi/onto/mesh/D000077270

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