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Concept information

Preferred term

Receptor, Transforming Growth Factor-beta Type I  

Type

  • Topical Descriptor

Entry terms

  • Activin Receptor like Kinase 5
  • Activin Receptor-like Kinase 5
  • Kinase, TbetaR-I
  • Receptor, TGF-beta Type I
  • Serine Threonine Protein Kinase Receptor R4
  • Serine-Threonine-Protein Kinase Receptor R4
  • TbetaR I Kinase
  • TbetaR-I Kinase
  • TGF beta Receptor Protein Kinase
  • TGF-beta Receptor Protein Kinase
  • TGF-beta RPK
  • TGF beta Type I Receptor
  • TGF-beta Type I Receptor
  • TGF beta Type I Receptors
  • TGF-beta Type I Receptors
  • TGFBR1
  • Transforming Growth Factor, beta Receptor 1
  • Transforming Growth Factor beta Receptor I
  • Type I TGF beta Receptor
  • Type I TGF-beta Receptor
  • Type I TGF beta Receptors
  • Type I TGF-beta Receptors

Scope note

  • A transmembrane serine-threonine kinase that forms a heteromeric complex with TYPE II TGF-BETA RECEPTORS to bind TGF-BETA and regulate a variety of physiological and pathological processes including CELL CYCLE ARREST; CELL PROLIFERATION; CELL DIFFERENTIATION; WOUND HEALING; EXTRACELLULAR MATRIX production, immunosuppression and ONCOGENESIS.

History note

  • 2019 (1994)

In other languages

URI

http://www.yso.fi/onto/mesh/D000077293

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