Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Niemann-Pick C1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Niemann-Pick C1 Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Virus > Niemann-Pick C1 Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Patched Receptors > Niemann-Pick C1 Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > Patched Receptors > Niemann-Pick C1 Protein

Preferred term

Niemann-Pick C1 Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • NPC1 Protein

Scope note

  • A transmembrane intracellular lipid transporter that helps trafficking lipids, particularly cholesterol, from late endosome/lysosome to the ER and plasma membrane. It may also play a role in other cellular cholesterol homeostasis and is an endosomal entry receptor for filoviruses including EBOLAVIRUS. Mutations in the NPC1 are associated with type C NIEMANN-PICK DISEASE.

History note

  • 2019

In other languages

URI

http://www.yso.fi/onto/mesh/D000077296

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/9/18, last modified 2/28/18