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Concept information

Preferred term

Agammaglobulinaemia Tyrosine Kinase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • B Cell Progenitor Kinase
  • Bruton's Tyrosine Kinase
  • Brutons Tyrosine Kinase
  • Bruton Tyrosine Kinase
  • Kinase, Bruton's Tyrosine
  • Tyrosine Kinase, Bruton's

Scope note

  • A non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. Mutations in the gene that encode this kinase are associated with X-LINKED AGAMMAGLOBULINEMIA.

History note

  • 2019 (1993)

In other languages

URI

http://www.yso.fi/onto/mesh/D000077329

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