Concept information
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Preferred term
Agammaglobulinaemia Tyrosine Kinase
Type
-
Topical Descriptor
Broader concept
Entry terms
- B Cell Progenitor Kinase
- Bruton's Tyrosine Kinase
- Brutons Tyrosine Kinase
- Bruton Tyrosine Kinase
- Kinase, Bruton's Tyrosine
- Tyrosine Kinase, Bruton's
Scope note
- A non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. Mutations in the gene that encode this kinase are associated with X-LINKED AGAMMAGLOBULINEMIA.
History note
- 2019 (1993)
In other languages
-
Finnish
-
Brutonin tyrosiinikinaasi
URI
http://www.yso.fi/onto/mesh/D000077329
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