Concept information
Preferred term
Leflunomide
Type
-
Topical Descriptor
Broader concept
Entry terms
- N-(4-Trifluoromethyphenyl)-5-methylisoxazole-4-carboxamide
Scope note
- An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.
History note
- 2019 (1985)
In other languages
-
Finnish
-
leflunomidum
-
Swedish
-
Arava
URI
http://www.yso.fi/onto/mesh/D000077339
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