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Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 2-Ring > Quinazolines > Lapatinib

Preferred term

Lapatinib  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • N-(3-chloro-4-(((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-methylsulfonyl)ethyl)amino)methyl) -2-furyl)-4-quinazolinamine

Scope note

  • A quinazoline derivative that inhibits EPIDERMAL GROWTH FACTOR RECEPTOR and HER2 (RECEPTOR, ERBB-2) tyrosine kinases. It is used for the treatment of advanced or metastatic breast cancer, where tumors overexpress HER2.

History note

  • 2019 (2004)

In other languages

URI

http://www.yso.fi/onto/mesh/D000077341

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