Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Peptides > Peptides, Cyclic > Eptifibatide
Polycyclic Compounds > Macrocyclic Compounds > Peptides, Cyclic > Eptifibatide

Preferred term

Eptifibatide  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 7H-Pyrrolo(2,1-g)(1,2,5,8,11,14,17,20)dithiahexaazacyclotricosine-17-acetic acid, 3-(aminocarbonyl)-11-(4-((aminoiminomethyl)amino)butyl)docosahydro-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxo-, (3R,11S,17S,20S,25aS)-
  • Epifibatide
  • Epifibratide

Scope note

  • Cyclic peptide that acts as a platelet glycoprotein IIB-IIIA antagonist, reversibly inhibiting the binding of FIBRINOGEN; VON WILLEBRAND FACTOR; and other adhesive molecules to the GPIIB-IIIA RECEPTORS of platelets. It is used in the management of UNSTABLE ANGINA and in patients undergoing coronary ANGIOPLASTY and stenting procedures.

History note

  • 2019 (1994)

In other languages

URI

http://www.yso.fi/onto/mesh/D000077542

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/9/18, last modified 4/29/19