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Pharmaceutical Preparations > Drug Combinations > Cilastatin, Imipenem Drug Combination
... > Lipids > Fatty Acids > Fatty Acids, Unsaturated > Fatty Acids, Monounsaturated > Cilastatin > Cilastatin, Imipenem Drug Combination
... > Polycyclic Compounds > Macrocyclic Compounds > Cycloparaffins > Cyclopropanes > Cilastatin > Cilastatin, Imipenem Drug Combination
... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Alicyclic > Cycloparaffins > Cyclopropanes > Cilastatin > Cilastatin, Imipenem Drug Combination
... > Inorganic Chemicals > Sulfur Compounds > beta-Lactams > Carbapenems > Thienamycins > Imipenem > Cilastatin, Imipenem Drug Combination
... > Organic Chemicals > Sulfur Compounds > beta-Lactams > Carbapenems > Thienamycins > Imipenem > Cilastatin, Imipenem Drug Combination
... > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Lactams > beta-Lactams > Carbapenems > Thienamycins > Imipenem > Cilastatin, Imipenem Drug Combination
... > Organic Chemicals > Amides > Lactams > beta-Lactams > Carbapenems > Thienamycins > Imipenem > Cilastatin, Imipenem Drug Combination
... > Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 2-Ring > beta-Lactams > Carbapenems > Thienamycins > Imipenem > Cilastatin, Imipenem Drug Combination

Preferred term

Cilastatin, Imipenem Drug Combination  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Cilastatin, Imipenem
  • Imipenem - Cilastatin
  • Imipenem Cilastatin
  • Imipenem-Cilastatin

Scope note

  • Combination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent.

History note

  • 2019 (1985)

In other languages

URI

http://www.yso.fi/onto/mesh/D000077728

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