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Organic Chemicals > Nitro Compounds > Nitrophenols > Tolcapone
... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Aromatic > Benzene Derivatives > Phenols > Nitrophenols > Tolcapone
... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Aromatic > Benzene Derivatives > Benzophenones > Tolcapone
Organic Chemicals > Ketones > Benzophenones > Tolcapone

Preferred term

Tolcapone  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 3,4 Dihydroxy 5' methyl 5 nitrobenzophenone
  • 3,4-Dihydroxy-5'-methyl-5-nitrobenzophenone
  • Ro 40 7592
  • Ro 40-7592
  • Ro 407592
  • SOM0226
  • Tasmar

Scope note

  • A benzophenone and nitrophenol compound that acts as an inhibitor of CATECHOL O-METHYLTRANSFERASE, an enzyme involved in the metabolism of DOPAMINE and LEVODOPA. It is used in the treatment of PARKINSON DISEASE in patients for whom levodopa is ineffective or contraindicated.

History note

  • 2019 (1990)

In other languages

URI

http://www.yso.fi/onto/mesh/D000077867

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