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Concept information

Preferred term

Pyruvate Dehydrogenase Acetyl-Transferring Kinase  

Type

  • Topical Descriptor

Entry terms

  • Dehydrogenase Kinase, Pyruvate
  • Kinase, PDH
  • Kinase, Pyruvate Dehydrogenase
  • PDH Kinase
  • Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase
  • Pyruvate Dehydrogenase Kinase
  • Pyruvate Dehydrogenase (Lipoamide) Kinase

Scope note

  • A pyruvate dehydrogenase kinase isozyme located in the mitochondria which converts PYRUVATE to ACETYL CoA in the CITRIC ACID CYCLE, phosphorylates SERINE residues on pyruvate dehydrogenase using ATP, and plays a key role in the regulation of GLUCOSE and fatty acid metabolism.

History note

  • 2021(1972)

URI

http://www.yso.fi/onto/mesh/D000081382

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