Concept information
Preferred term
Angiotensin-Converting Enzyme 2
Type
-
Topical Descriptor
Broader concept
Entry terms
- ACE2 Angiotensin Converting Enzyme Protein 2
- ACE2 Angiotensin-Converting Enzyme Protein 2
- ACE2 Enzyme
- ACE2 Protein
- ACE Related Carboxypeptidase
- ACE-Related Carboxypeptidase
- Angiotensin Converting Enzyme 2
- Angiotensin Converting Enzyme Related Carboxypeptidase
- Angiotensin-Converting Enzyme-Related Carboxypeptidase
- Carboxypeptidase, ACE-Related
- Carboxypeptidase, Angiotensin-Converting Enzyme-Related
Scope note
- A transmembrane glycoprotein with an extracellular catalytic domain which functions as a carboxypeptidase. It cleaves a single C-terminal residue from a distinct range of substrates. The catalytic efficiency is 400-fold higher with ANGIOTENSIN II as a substrate than with ANGIOTENSIN I. Angiotensin-converting enzyme 2 is also is a functional receptor for the spike glycoprotein (SPIKE PROTEIN, CORONAVIRUS) of the CORONAVIRUSES SARS-COV, SARS-COV2, and HCOV-NL63.
History note
- 2021 (2000)
In other languages
-
Finnish
-
angiotensiiniä muuntava entsyymi 2
-
angiotensiiniä muuttava entsyymi 2
-
Swedish
-
ACE-relaterat karboxypeptidas
-
ACE2-enzym
-
ACE2-protein
URI
http://www.yso.fi/onto/mesh/D000085962
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}