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... > Cells > Cellular Structures > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Nuclear Bodies > Promyelocytic Leukemia Nuclear Bodies
... > Fluids and Secretions > Body Fluids > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Nuclear Bodies > Promyelocytic Leukemia Nuclear Bodies
... > Tissues > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Nuclear Bodies > Promyelocytic Leukemia Nuclear Bodies

Preferred term

Promyelocytic Leukemia Nuclear Bodies  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Nuclear Bodies, PML
  • Nuclear Body, PML
  • PML Bodies
  • PML Body
  • PML NBs
  • PML Nuclear Bodies
  • PML Nuclear Body
  • Promyelocytic Leukemia Nuclear Body
  • Promyelocytic Leukemia Protein Bodies
  • Promyelocytic Leukemia Protein Body

Scope note

  • Spherical intranuclear membraneless bodies nucleated by PROMYELOCYTIC LEUKEMIA PROTEIN and various other proteins containing small ubiquitin-related modifier (SUMO) interaction motif (SIM) and/or sumoylated proteins (e.g., Sp100 protein). Promyelocytic leukemia nuclear bodies regulate posttranslational modifications of partner proteins (e.g., SUMOYLATION) which in turn lead to modulation of various biological processes.

History note

  • 2022

In other languages

URI

http://www.yso.fi/onto/mesh/D000088182

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