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Cell Physiological Phenomena > Cellular Senescence > Senescence-Associated Secretory Phenotype
Physiological Phenomena > Growth and Development > Aging > Cellular Senescence > Senescence-Associated Secretory Phenotype

Preferred term

Senescence-Associated Secretory Phenotype  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • SASP, Senescent Cell
  • SASPs, Senescent Cell
  • Senescent Cell SASP
  • Senescent Cell SASPs

Scope note

  • A paracrine pro-inflammatory phenotype developed in senescing cells. The senescence-associated secretory phenotype (SASP) results from the inflammatory, proteolytic and growth factor enriched SECRETOME of many types of senescent cells which leads to tissue repair or tissue and organ damage over time and links SASP to age-related disorders.

History note

  • 2022; use CELLULAR SENESCENCE 2018-2021

In other languages

URI

http://www.yso.fi/onto/mesh/D000089262

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RDF/XML TURTLE JSON-LD Created 7/9/21, last modified 7/7/21