Concept information
Preferred term
Phase Variation
Type
-
Topical Descriptor
Broader concept
Entry terms
- Phasevarion
- Phasevarions
Scope note
- An adaptive mechanism used by microbes to avoid detection by the host or adapt to changes in environment by randomly and rapidly switch on and off of a gene by various mechanisms between on and off phases. For instance, drug tolerant MYCOBACTERIUM TUBERCULOSIS arises through rapid reversible mutations in the glpK gene through phase variation.
History note
- 2022
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000090502
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