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Concept information

Preferred term

Delta-5 Fatty Acid Desaturase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 5 Desaturase, Delta
  • Acid Delta-5-Desaturase, Fatty
  • Delta 5 Desaturase
  • Delta-5-Desaturase, Fatty Acid
  • Delta 5 FADase
  • Delta-5-FADase
  • Desaturase, Delta 5
  • Fatty Acid Delta 5 Desaturase
  • Fatty Acid Delta-5-Desaturase

Scope note

  • A fatty acid desaturase that is a rate-limiting enzyme for the conversion from dihomo-gamma-linolenic acid and EICOSATETRAENOATE (ETA) in the synthesis of ARACHIDONIC ACID and EICOSAPENTAENOATE (EPA). It is also involved in the biosynthesis of unsaturated fatty acids from the polyunsaturated fatty acids (PUFA), LINOLEIC ACID (LA), and ALPHA LINOLENIC ACID (ALA) precursors and plays an important role in the metabolism of inflammatory lipids including PROSTAGLANDIN E2.

History note

  • 2022 (1981)

In other languages

URI

http://www.yso.fi/onto/mesh/D000090943

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