Concept information
Preferred term
M Cells
Type
-
Topical Descriptor
Broader concept
Entry terms
- Cell, Microfold
- Cells, Microfold
- Microfold Cell
- Microfold Cells
Scope note
- A distinct lineage of epithelial cells, present in MUCOSAL TISSUE, that is responsible for the immune sensing and capture of luminal bacteria and other microparticles. They deliver these microparticles, via TRANSCYTOSIS, to lymphoid tissue for efficient mucosal as well as systemic immune responses. Inflammation-induced M cells arising in response to inflammatory conditions may provide microbial access to tissues without normal M cell-associated immune surveillance tissue.
History note
- 2023
URI
http://www.yso.fi/onto/mesh/D000092303
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