Concept information
Preferred term
Medium Spiny Neurons
Type
-
Topical Descriptor
Broader concept
Entry terms
- Striatal Medium Sized Spiny Neurons
- Striatal Medium-Sized Spiny Neurons
Scope note
- Medium sized, inhibitory GABAergic neurons in the CORPUS STRIATUM with highly developed dendritic trees. They are divided into neurons expressing DOPAMINE D1 RECEPTORS which project preferentially to the SUBSTANTIA NIGRA PARS RETICULATA and neurons expressing DOPAMINE D2 RECEPTORS which project preferentially to the lateral part of the GLOBUS PALLIDUS. Medium spiny neurons are preferentially lost in HUNTINGTON DISEASE.
History note
- 2023
In other languages
-
Finnish
-
striatumin keskikokoiset inhibitoriset GABA-ergiset hermosolut
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000094242
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