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Concept information

Preferred term

Piwi-Interacting RNA  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • piRNA
  • piRNAs
  • RNA, Piwi Interacting
  • RNA, Piwi-Interacting

Scope note

  • A class of small RNAs that are 24–31 nucleotides in length. They associate with the PIWI SUBFAMILY OF ARGONAUTE PROTEINS to form effector complexes known as piRNA-induced silencing complexes, which repress transposons via transcriptional or posttranscriptional mechanisms and maintain germline genome integrity. In addition to their role in transposon silencing, piRNAs in diverse organisms function in the regulation of cellular genes.

History note

  • 2023; use RNA,SMALL INTERFERING 2008-2022

In other languages

URI

http://www.yso.fi/onto/mesh/D000094322

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