Concept information
Preferred term
T-Cell Exhaustion
Type
-
Topical Descriptor
Broader concept
Entry terms
- Exhaustions, T-Lymphocyte
- Exhaustion, T-Lymphocyte
- T Lymphocyte Exhaustion
- T-Lymphocyte Exhaustion
- T-Lymphocyte Exhaustions
Scope note
- Progressive deterioration of T-cell function due to chronic antigen stimulation and inflammatory signals, e.g., CHRONIC INFECTION and CANCER. T-cell exhaustion is characterized by weakened immune system, e.g., dysfunctional MEMORY T CELLS differentiation and EPIGENETIC REPRESSION of IMMUNOLOGIC MEMORY effector functions.
History note
- 2023
In other languages
-
Finnish
-
T-solujen väsyminen
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000094383
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