Concept information
Preferred term
DNA Polymerase iota
Type
-
Topical Descriptor
Broader concept
Entry terms
- POL iota
- POLiota
- RAD30B
Scope note
- A highly error-prone DNA polymerase. It is a member of the Y-family of DNA polymerases that are DNA DAMAGE tolerant and involved in TRANSLESION DNA SYNTHESIS. DNA polymerase iota is an orthologue of yeast Rad30. Its replication fidelity is template dependent and favors Hoogsteen base-pairing at its active site.
History note
- 2023 (2000)
In other languages
-
Finnish
-
DNA-polymeraasi iota
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000094769
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