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... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Aromatic > Polycyclic Aromatic Hydrocarbons > Naphthalenes > Naphthoquinones > Pradimicins and Benanomicins
Polycyclic Compounds > Polycyclic Aromatic Hydrocarbons > Naphthalenes > Naphthoquinones > Pradimicins and Benanomicins
Organic Chemicals > Quinones > Naphthoquinones > Pradimicins and Benanomicins
Organic Chemicals > Lactones > Polyketides > Pradimicins and Benanomicins
Polycyclic Compounds > Macrocyclic Compounds > Polyketides > Pradimicins and Benanomicins
Carbohydrates > Glycosides > Aminoglycosides > Anthracyclines > Pradimicins and Benanomicins
... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Aromatic > Polycyclic Aromatic Hydrocarbons > Naphthacenes > Anthracyclines > Pradimicins and Benanomicins
Polycyclic Compounds > Polycyclic Aromatic Hydrocarbons > Naphthacenes > Anthracyclines > Pradimicins and Benanomicins

Preferred term

Pradimicins and Benanomicins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Benanomicins and Pradimicins
  • Pradimicin Like Polyketides
  • Pradimicin-Like Polyketides
  • Pradimicin Type Polyphenols
  • Pradimicin-Type Polyphenols

Scope note

  • Polycyclic aromatic polyketides with pentacyclic angular dihydrobenzo(a)naphthacenequinone skeletons. Pradimicin- and related benanomicin-type polyphenols are produced by Actinobacteria, e.g., ACTINOMADURA, using type II polyketide synthase involving condensation of one acetyl-CoA and nine malonyl-CoA. Pradimicins and benanomicins have an amino acid (e.g., D-ALANINE) and often a 5-O-sugar and bind to terminal D-mannosides of the cell wall of various fungi, e.g., CANDIDA. In addition to antifungal activity many pradimicins and benanomicins have anti-HIV activities.

History note

  • 2024

In other languages

URI

http://www.yso.fi/onto/mesh/D000095643

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