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Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Neuroligins
... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > Cell Adhesion Molecules, Neuronal > Neural Cell Adhesion Molecules > Neuroligins
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > Cell Adhesion Molecules, Neuronal > Neural Cell Adhesion Molecules > Neuroligins
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Cell Adhesion Molecules > Cell Adhesion Molecules, Neuronal > Neural Cell Adhesion Molecules > Neuroligins
... > Biological Factors > Antigens > Antigens, Surface > Cell Adhesion Molecules > Cell Adhesion Molecules, Neuronal > Neural Cell Adhesion Molecules > Neuroligins

Preferred term

Neuroligins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Neuroligin

Scope note

  • Postsynaptic cell-adhesion molecules that bind presynaptic NEUREXINS to form calcium-dependent trans-synaptic adhesions. Neuroligins recruit synaptic scaffolding proteins (e.g., PSD-95) via their PDZ DOMAIN. The distribution and interaction with neurexins are regulated by ALTERNATIVE SPLICING. Alterations in genes encoding neuroligins or neurexins are associated with cognitive diseases such as AUTISM SPECTRUM DISORDER.

History note

  • 2024

In other languages

URI

http://www.yso.fi/onto/mesh/D000096785

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RDF/XML TURTLE JSON-LD Created 7/26/23, last modified 6/1/23