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Concept information

Preferred term

HLA-E Antigens  

Type

  • Topical Descriptor

Entry terms

  • HLA E Antigens

Scope note

  • Class I human histocompatibility (HLA) antigens encoded by genes at the E locus on chromosome 6. They bind a restricted subset of peptides derived from the leader peptides of other class I molecules. They primarily are involved with down-regulating cytolytic activity of NK CELLS and restricting non-canonical CD8-POSITIVE T LYMPHOCYTES.

History note

  • 2024 (1988)

In other languages

URI

http://www.yso.fi/onto/mesh/D000097625

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