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Concept information

Preferred term

Adjuvants, Immunologic  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Adjuvant, Immunologic
  • Adjuvant, Immunological
  • Adjuvants, Immunological
  • Immunoactivators
  • Immunoadjuvant
  • Immunoadjuvants
  • Immunologic Adjuvant
  • Immunologic Adjuvants
  • Immunological Adjuvant
  • Immunological Adjuvants
  • Immunopotentiator
  • Immunopotentiators
  • Immunostimulant
  • Immunostimulants

Scope note

  • Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.

History note

  • 65

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URI

http://www.yso.fi/onto/mesh/D000276

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