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Concept information

Preferred term

Alkylating Agents  

Type

  • Topical Descriptor

Entry terms

  • Agent, Alkylating
  • Alkylating Agent
  • Alkylator
  • Alkylators

Scope note

  • Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.

History note

  • 66(64)

In other languages

URI

http://www.yso.fi/onto/mesh/D000477

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