Concept information
Preferred term
alpha-MSH
Type
-
Topical Descriptor
Broader concept
Entry terms
- Acetylated ACTH (1-13)NH2
- alpha Intermedin
- alpha Melanocyte Stimulating Hormone
- alpha-Melanocyte-Stimulating Hormone
- alpha Melanotropin
- alpha-Melanotropin
- Hormone, alpha-Melanocyte-Stimulating
- Intermedin, alpha
- MSH, alpha
Scope note
- A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of MELANIN in MELANOCYTES in mammals and MELANOPHORES in lower vertebrates.
History note
- 1988 (1981)
URI
http://www.yso.fi/onto/mesh/D000521
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