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Concept information

Preferred term

alpha-MSH  

Type

  • Topical Descriptor

Entry terms

  • Acetylated ACTH (1-13)NH2
  • alpha Intermedin
  • alpha Melanocyte Stimulating Hormone
  • alpha-Melanocyte-Stimulating Hormone
  • alpha Melanotropin
  • alpha-Melanotropin
  • Hormone, alpha-Melanocyte-Stimulating
  • Intermedin, alpha
  • MSH, alpha

Scope note

  • A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of MELANIN in MELANOCYTES in mammals and MELANOPHORES in lower vertebrates.

History note

  • 1988 (1981)

In other languages

URI

http://www.yso.fi/onto/mesh/D000521

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