Concept information
Preferred term
5-Aminolevulinate Synthetase
Type
-
Topical Descriptor
Broader concept
Entry terms
- 5 Aminolevulinate Synthase
- 5-Aminolevulinate Synthase
- Acid Synthetase, Aminolevulinic
- Acid Synthetase, delta-Aminolevulinic
- Aminolevulinic Acid Synthetase
- delta Aminolevulinate Synthase
- delta-Aminolevulinate Synthase
- delta Aminolevulinic Acid Synthetase
- delta-Aminolevulinic Acid Synthetase
- Synthase, 5-Aminolevulinate
- Synthase, delta-Aminolevulinate
- Synthetase, Aminolevulinic Acid
- Synthetase, delta-Aminolevulinic Acid
Scope note
- An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37.
History note
- 98(72)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000624
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