Concept information
Preferred term
Anaphylatoxins
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Anaphylatoxin
Scope note
- Serum peptides derived from certain cleaved COMPLEMENT PROTEINS during COMPLEMENT ACTIVATION. They induce smooth MUSCLE CONTRACTION; mast cell HISTAMINE RELEASE; PLATELET AGGREGATION; and act as mediators of the local inflammatory process. The order of anaphylatoxin activity from the strongest to the weakest is C5a, C3a, C4a, and C5a des-arginine.
History note
- 90(77); was see under PEPTIDES 1977-89
In other languages
-
Finnish
-
anafylatoksiini
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000706
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}