Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Serpins > Angiotensinogen
Amino Acids, Peptides, and Proteins > Peptides > Serpins > Angiotensinogen
... > Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Enzyme Inhibitors > Protease Inhibitors > Serine Proteinase Inhibitors > Serpins > Angiotensinogen
Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Angiotensinogen
Biological Factors > Inflammation Mediators > Autacoids > Angiotensins > Angiotensinogen
Amino Acids, Peptides, and Proteins > Peptides > Oligopeptides > Angiotensins > Angiotensinogen
... > Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Neuropeptides > Angiotensins > Angiotensinogen
Amino Acids, Peptides, and Proteins > Peptides > Neuropeptides > Angiotensins > Angiotensinogen
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Peptide Hormones > Angiotensins > Angiotensinogen
Amino Acids, Peptides, and Proteins > Peptides > Peptide Hormones > Angiotensins > Angiotensinogen

Preferred term

Angiotensinogen  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Hypertensinogen
  • Proangiotensin
  • Renin Substrate
  • Renin-Substrate
  • Serpin A8
  • SERPINA8

Scope note

  • An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver in response to lowered blood pressure and secreted into blood circulation. Angiotensinogen is the inactive precursor of the ANGIOTENSINS produced in the body by successive enzyme cleavages. Cleavage of angiotensinogen by RENIN yields the decapeptide ANGIOTENSIN I. Further cleavage of angiotensin I (by ANGIOTENSIN CONVERTING ENZYME) yields the potent vasoconstrictor octapeptide ANGIOTENSIN II; and then, via other enzymes, other angiotensins also involved in the hemodynamic-regulating RENIN-ANGIOTENSIN SYSTEM.

History note

  • 87(75); was see under ANGIOTENSINS 1975-86

In other languages

URI

http://www.yso.fi/onto/mesh/D000808

Download this concept:

RDF/XML TURTLE JSON-LD Created 11/19/74, last modified 6/9/20