Concept information
Preferred term
Antibody Affinity
Type
-
Topical Descriptor
Broader concept
Entry terms
- Affinities, Antibody
- Affinity, Antibody
- Antibody Affinities
Note
- do not confuse with BINDING SITES, ANTIBODY or ANTIGENIC DETERMINANTS
Scope note
- A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
History note
- 79
In other languages
-
Finnish
-
vasta-aineen affiniteetti
-
Swedish
URI
http://www.yso.fi/onto/mesh/D000915
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