Concept information
Preferred term
Antibody-Dependent Cell Cytotoxicity
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- ADCC
- Antibody-Dependent Cell Cytotoxicities
- Antibody-Dependent Cell Cytoxicities
- Antibody-Dependent Cell Cytoxicity
- Cell Cytotoxicities, Antibody-Dependent
- Cell Cytotoxicity, Antibody-Dependent
- Cell Cytoxicities, Antibody-Dependent
- Cell Cytoxicity, Antibody Dependent
- Cell Cytoxicity, Antibody-Dependent
- Cytotoxicities, Antibody-Dependent Cell
- Cytotoxicity, Antibody Dependent Cell
- Cytotoxicity, Antibody-Dependent Cell
- Cytoxicities, Antibody-Dependent Cell
- Cytoxicity, Antibody-Dependent Cell
Scope note
- The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a "killer" cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent.
History note
- 78
In other languages
-
Finnish
-
Swedish
-
Antikroppsberoende cytotoxicitet
URI
http://www.yso.fi/onto/mesh/D000920
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