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Concept information

Preferred term

Antidepressive Agents, Tricyclic  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Agent, Tricyclic Antidepressive
  • Antidepressant Drugs, Tricyclic
  • Antidepressant Drug, Tricyclic
  • Antidepressants, Tricyclic
  • Antidepressant, Tricyclic
  • Antidepressive Agent, Tricyclic
  • Drugs, Tricyclic Antidepressant
  • Drug, Tricyclic Antidepressant
  • Tricyclic Antidepressant
  • Tricyclic Antidepressant Drug
  • Tricyclic Antidepressant Drugs
  • Tricyclic Antidepressants
  • Tricyclic Antidepressive Agent
  • Tricyclic Antidepressive Agents

Scope note

  • Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.

History note

  • 75

In other languages

URI

http://www.yso.fi/onto/mesh/D000929

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