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Concept information

Preferred term

Apolipoproteins B  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Apo B
  • Apo-B
  • ApoB

Scope note

  • Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms, apolipoprotein B-100 and apolipoprotein B-48, both derived from a single gene. ApoB-100 expressed in the liver is found in low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL). ApoB-48 expressed in the intestine is found in CHYLOMICRONS. They are important in the biosynthesis, transport, and metabolism of triacylglycerol-rich lipoproteins. Plasma Apo-B levels are high in atherosclerotic patients but non-detectable in ABETALIPOPROTEINEMIA.

History note

  • 85; APOLIPOPROTEIN B was see APOLIPOPROTEINS B 1985-93

In other languages

URI

http://www.yso.fi/onto/mesh/D001055

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