Concept information
Preferred term
Apolipoproteins B
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Apo B
- Apo-B
- ApoB
Scope note
- Major structural proteins of triacylglycerol-rich LIPOPROTEINS. There are two forms, apolipoprotein B-100 and apolipoprotein B-48, both derived from a single gene. ApoB-100 expressed in the liver is found in low-density lipoproteins (LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL). ApoB-48 expressed in the intestine is found in CHYLOMICRONS. They are important in the biosynthesis, transport, and metabolism of triacylglycerol-rich lipoproteins. Plasma Apo-B levels are high in atherosclerotic patients but non-detectable in ABETALIPOPROTEINEMIA.
History note
- 85; APOLIPOPROTEIN B was see APOLIPOPROTEINS B 1985-93
In other languages
-
Finnish
-
apolipoproteiini B
-
Swedish
URI
http://www.yso.fi/onto/mesh/D001055
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