Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Lipoproteins > Apolipoproteins > Apolipoproteins E
Lipids > Lipoproteins > Apolipoproteins > Apolipoproteins E
Amino Acids, Peptides, and Proteins > Proteins > Apoproteins > Apolipoproteins > Apolipoproteins E

Preferred term

Apolipoproteins E  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Apo E
  • Apo-E
  • ApoE

Scope note

  • A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.

History note

  • 1985; for APOLIPOPROTEIN E ISOPROTEINS use APOLIPOPROTEINS E 1985-2006 & use APOLIPOPROTEINS 1983-1984

In other languages

URI

http://www.yso.fi/onto/mesh/D001057

Download this concept:

RDF/XML TURTLE JSON-LD Created 5/25/84, last modified 7/5/06