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Concept information

Preferred term

Arachidonate 12-Lipoxygenase  

Type

  • Topical Descriptor

Entry terms

  • 12 Lipoxygenase
  • 12-Lipoxygenase
  • 12-Lipoxygenase, Arachidonic Acid
  • Arachidonic Acid 12 Lipoxygenase
  • Arachidonic Acid 12-Lipoxygenase

Scope note

  • An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in PLATELETS.

History note

  • 91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90

In other languages

URI

http://www.yso.fi/onto/mesh/D001092

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