Concept information
Preferred term
Arachidonate 5-Lipoxygenase
Type
-
Topical Descriptor
Broader concept
Entry terms
- 5 Lipoxygenase
- 5-Lipoxygenase
- 5-Lipoxygenase, Arachidonic Acid
- Arachidonic Acid 5 Lipoxygenase
- Arachidonic Acid 5-Lipoxygenase
- Leukotriene A4 Synthase
- Leukotriene A4 Synthetase
- Leukotriene A Synthase
- LTA4 Synthase
- Synthase, Leukotriene A
- Synthase, Leukotriene A4
- Synthase, LTA4
- Synthetase, Leukotriene A4
Scope note
- An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes.
History note
- 91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90
In other languages
-
Finnish
-
arakidonaatti-5-lipo-oksigenaasi
-
Swedish
URI
http://www.yso.fi/onto/mesh/D001094
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