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Concept information

Preferred term

Arachidonate 5-Lipoxygenase  

Type

  • Topical Descriptor

Entry terms

  • 5 Lipoxygenase
  • 5-Lipoxygenase
  • 5-Lipoxygenase, Arachidonic Acid
  • Arachidonic Acid 5 Lipoxygenase
  • Arachidonic Acid 5-Lipoxygenase
  • Leukotriene A4 Synthase
  • Leukotriene A4 Synthetase
  • Leukotriene A Synthase
  • LTA4 Synthase
  • Synthase, Leukotriene A
  • Synthase, Leukotriene A4
  • Synthase, LTA4
  • Synthetase, Leukotriene A4

Scope note

  • An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes.

History note

  • 91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90

In other languages

URI

http://www.yso.fi/onto/mesh/D001094

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