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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Aromatase
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Aromatase
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Aromatase
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 19 > Aromatase
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 19 > Aromatase
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 19 > Aromatase

Preferred term

Aromatase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Androstenedione Aromatase
  • Aromatase, Androstenedione
  • CYP 19
  • CYP19
  • CYP19 Protein
  • Cytochrome P450 19
  • Cytochrome P-450(AROM)
  • Cytochrome P 450 CYP19
  • Cytochrome P-450 CYP19
  • Estrogen Synthase
  • Estrogen Synthetase
  • P450AROM
  • Protein, CYP19

Scope note

  • An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system.

History note

  • 86(75); was see under OXIDOREDUCTASES 1975-85

In other languages

URI

http://www.yso.fi/onto/mesh/D001141

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