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Concept information

Preferred term

Aryl Hydrocarbon Hydroxylases  

Type

  • Topical Descriptor

Entry terms

  • Microsomal Monooxygenases
  • Monooxygenases, Microsomal

Scope note

  • A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.

History note

  • 75

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URI

http://www.yso.fi/onto/mesh/D001189

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