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Concept information

Preferred term

Autophagy  

Type

  • Topical Descriptor

Entry terms

  • Autophagocytosis
  • Autophagy, Cellular
  • Cellular Autophagy

Note

  • general or unspecified; note specifics; do not confuse with AUTOPHAGIC CELL DEATH, a form of regulated cell death

Scope note

  • The segregation and degradation of various cytoplasmic constituents via engulfment by MULTIVESICULAR BODIES; VACUOLES; or AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.

History note

  • 2006(1979)

In other languages

URI

http://www.yso.fi/onto/mesh/D001343

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