Concept information
Preferred term
Autophagy
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Autophagocytosis
- Autophagy, Cellular
- Cellular Autophagy
Note
- general or unspecified; note specifics; do not confuse with AUTOPHAGIC CELL DEATH, a form of regulated cell death
Scope note
- The segregation and degradation of various cytoplasmic constituents via engulfment by MULTIVESICULAR BODIES; VACUOLES; or AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.
History note
- 2006(1979)
URI
http://www.yso.fi/onto/mesh/D001343
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