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Concept information

Amino Acids, Peptides, and Proteins > Amino Acids > Aminobutyrates > gamma-Aminobutyric Acid > Baclofen
... > Organic Chemicals > Carboxylic Acids > Acids, Acyclic > Butyrates > Aminobutyrates > gamma-Aminobutyric Acid > Baclofen
... > Lipids > Fatty Acids > Fatty Acids, Volatile > Butyrates > Aminobutyrates > gamma-Aminobutyric Acid > Baclofen

Preferred term

Baclofen  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Baclophen
  • beta-(Aminomethyl)-4-chlorobenzenepropanoic Acid
  • beta-(p-Chlorophenyl)-gamma-aminobutyric Acid
  • Chlorophenyl GABA
  • GABA, Chlorophenyl
  • PCP-GABA

Scope note

  • A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.

History note

  • 80(75); was see under AMINOBUTYRIC ACIDS 1975-79

In other languages

URI

http://www.yso.fi/onto/mesh/D001418

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