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Concept information

Preferred term

Anion Exchange Protein 1, Erythrocyte  

Type

  • Topical Descriptor

Entry terms

  • AE1 Anion Exchanger
  • AE1 Chloride Bicarbonate Exchanger
  • AE1 Chloride-Bicarbonate Exchanger
  • AE1 Cl HCO3 Exchanger
  • AE1 Cl- HCO3- Exchanger
  • AE1 Gene Product
  • Anion Exchanger 1
  • Anion Exchanger, Erythrocyte
  • Anion Transport Protein, Erythrocyte
  • Antigen, CD233
  • Antigens, CD233
  • Band 3 Anion Transport Protein
  • Band 3 Protein
  • Band III Protein
  • Capnophorin
  • CD233 Antigen
  • CD233 Antigens
  • Chloride-Bicarbonate Exchanger, AE1
  • EPB3 Protein
  • Erythrocyte Anion Exchanger
  • Erythrocyte Anion Transport Protein
  • Erythrocyte Membrane Anion Transport Protein
  • Erythrocyte Membrane Band 3 Protein
  • Erythrocyte Membrane Protein Band 3, Diego Blood Group
  • Exchanger 1, Anion
  • Protein Band 3
  • Protein, EPB3
  • SLC4A1 Protein
  • Solute Carrier Family 4, Anion Exchanger, Member 1
  • Solute Carrier Family 4 Member 1

Scope note

  • A major integral transmembrane protein of the ERYTHROCYTE MEMBRANE. It is the anion exchanger responsible for electroneutral transporting in CHLORIDE IONS in exchange of BICARBONATE IONS allowing CO2 uptake and transport from tissues to lungs by the red blood cells. Genetic mutations that result in a loss of the protein function have been associated with type 4 HEREDITARY SPHEROCYTOSIS.

History note

  • 2002(1984); for AE1 ANION EXCHANGER, AE1 CHLORIDE-BICARBONATE EXCHANGER, AE1 Cl- HCO3- EXCHANGER & AE1 GENE PRODUCT use CHLORIDE-BICARBONATE ANTIPORTERS (NM) 1998-2001

In other languages

URI

http://www.yso.fi/onto/mesh/D001457

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