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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Glycoside Hydrolases > Hexosaminidases > beta-N-Acetylhexosaminidases

Preferred term

beta-N-Acetylhexosaminidases  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • beta Hexosaminidase
  • beta-Hexosaminidase
  • beta N Acetyl D hexosaminidase
  • beta-N-Acetyl-D-hexosaminidase
  • beta N Acetyl hexosaminidase
  • beta N Acetylhexosaminidase
  • beta-N-Acetyl-hexosaminidase
  • beta-N-Acetylhexosaminidase
  • N Acetyl beta D hexosaminidase
  • N-Acetyl-beta-D-hexosaminidase

Note

  • do not confuse with ACETYLGLUCOSAMINIDASE; /defic: consider also TAY SACHS DISEASE and SANDHOFF DISEASE

Scope note

  • A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES. Two specific mammalian isoenzymes of beta-N-acetylhexoaminidase are referred to as HEXOSAMINIDASE A and HEXOSAMINIDASE B. Deficiency of the type A isoenzyme causes TAY-SACHS DISEASE, while deficiency of both A and B isozymes causes SANDHOFF DISEASE. The enzyme has also been used as a tumor marker to distinguish between malignant and benign disease.

History note

  • 2008(1988)

In other languages

URI

http://www.yso.fi/onto/mesh/D001619

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