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Concept information

Metabolism > Pharmacokinetics > Biotransformation
Physiological Phenomena > Pharmacological and Toxicological Phenomena > Pharmacokinetics > Biotransformation

Preferred term

Biotransformation  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Note

  • restrict to chemical changes of exogenous substances; IM general only; coordinate NIM with specific drug /pharmacokin (IM) or /metab; do not confuse with BIODEGRADATION, ENVIRONMENTAL

Scope note

  • The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.

History note

  • 70(66)

In other languages

URI

http://www.yso.fi/onto/mesh/D001711

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