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... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Aromatic > Polycyclic Aromatic Hydrocarbons > Phenanthrenes > Morphinans > Buprenorphine
Polycyclic Compounds > Polycyclic Aromatic Hydrocarbons > Phenanthrenes > Morphinans > Buprenorphine
Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 4 or More Rings > Morphinans > Buprenorphine
Heterocyclic Compounds > Alkaloids > Opiate Alkaloids > Morphinans > Buprenorphine
Heterocyclic Compounds > Heterocyclic Compounds, Bridged-Ring > Morphinans > Buprenorphine

Preferred term

Buprenorphine  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • 6029 M
  • 6029-M
  • 6029M
  • Buprenex
  • Buprenorphine Hydrochloride
  • Hydrochloride, Buprenorphine
  • Prefin
  • Subutex

Note

  • for buprenorphine maintenance treatment, coordinate with OPIATE SUBSTITUTION TREATMENT

Scope note

  • A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.

History note

  • 87(79); was see under MORPHINANS 1979-86

In other languages

URI

http://www.yso.fi/onto/mesh/D002047

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