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... > Organic Chemicals > Carboxylic Acids > Acids, Acyclic > Imino Acids > Proline > Captopril
Organic Chemicals > Imines > Imino Acids > Proline > Captopril
... > Amino Acids, Peptides, and Proteins > Amino Acids > Amino Acids, Cyclic > Imino Acids > Proline > Captopril

Preferred term

Captopril  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline

Scope note

  • A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.

History note

  • 86(80); was see under PROLINE 1980-85; SQ 14225 was see CAPTOPRIL 1980-93

In other languages

URI

http://www.yso.fi/onto/mesh/D002216

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