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Cardiovascular Diseases > Heart Diseases > Carcinoid Heart Disease
... > Neoplasms > Neoplasms by Histologic Type > Neoplasms, Glandular and Epithelial > Carcinoma > Adenocarcinoma > Carcinoid Tumor > Malignant Carcinoid Syndrome > Carcinoid Heart Disease
... > Neoplasms > Neoplasms by Histologic Type > Neoplasms, Germ Cell and Embryonal > Neuroectodermal Tumors > Neuroendocrine Tumors > Carcinoid Tumor > Malignant Carcinoid Syndrome > Carcinoid Heart Disease
... > Neoplasms > Neoplasms by Histologic Type > Neoplasms, Nerve Tissue > Neuroectodermal Tumors > Neuroendocrine Tumors > Carcinoid Tumor > Malignant Carcinoid Syndrome > Carcinoid Heart Disease

Preferred term

Carcinoid Heart Disease  

Type

  • Topical Descriptor

Broader concept

Scope note

  • Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.

History note

  • 91(75)(64-72); was see under MALIGNANT CARCINOID SYNDROME 1964-90 (Prov 1964-72)

In other languages

URI

http://www.yso.fi/onto/mesh/D002275

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