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Investigative Techniques > Chemistry Techniques, Analytical > Ultracentrifugation > Centrifugation, Density Gradient > Centrifugation, Isopycnic
Investigative Techniques > Centrifugation > Ultracentrifugation > Centrifugation, Density Gradient > Centrifugation, Isopycnic

Preferred term

Centrifugation, Isopycnic  

Type

  • Topical Descriptor

Broader concept

Scope note

  • A technique used to separate particles according to their densities in a continuous density gradient. The sample is usually mixed with a solution of known gradient materials and subjected to centrifugation. Each particle sediments to the position at which the gradient density is equal to its own. The range of the density gradient is usually greater than that of the sample particles. It is used in purifying biological materials such as proteins, nucleic acids, organelles, and cell types.

History note

  • 91(75); was see under CENTRIFUGATION, DENSITY GRADIENT 1975-90

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URI

http://www.yso.fi/onto/mesh/D002500

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