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Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Cholesterol 7-alpha-Hydroxylase
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Cholesterol 7-alpha-Hydroxylase
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Cholesterol 7-alpha-Hydroxylase
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 7 > Cholesterol 7-alpha-Hydroxylase
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 7 > Cholesterol 7-alpha-Hydroxylase
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 7 > Cholesterol 7-alpha-Hydroxylase

Preferred term

Cholesterol 7-alpha-Hydroxylase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Cholesterol 7alpha Hydroxylase
  • Cholesterol 7alpha-Hydroxylase
  • Cholesterol 7 alpha Monooxygenase
  • Cholesterol 7-alpha-Monooxygenase
  • Cholesterol 7 Hydroxylase
  • Cholesterol-7-Hydroxylase
  • CYP 7
  • CYP7
  • CYP 7A
  • CYP7A
  • Cytochrome P450 7
  • Cytochrome P 450 CYP7
  • Cytochrome P-450 CYP7

Scope note

  • A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.

History note

  • 2003 (1975)

In other languages

URI

http://www.yso.fi/onto/mesh/D002790

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