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Concept information

Preferred term

Cimetidine  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine

Scope note

  • A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.

History note

  • 84(78); was see under GUANIDINES 1978-83

In other languages

URI

http://www.yso.fi/onto/mesh/D002927

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